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Type I collagen is an interstitial fibrillar collagen consisting of two identical a1(I) chains and one a2(I) chain. It is the most abundant collagen type and is found in most connective tissues such as skin, bone, tendon, ligament, and heart. Many tissues contain heterotypic fibrils meaning that two or more distinct collagen types coexist. For example, most connective tissues (with the exception of bone) contain heterotypic fibrils of type I and III collagen, although type III collagen is a minor component.
The Porcine Type I Collagen Detection Kit is designed to quantify the amount of type I collagen from porcine cell and/or tissue culture or from tissue specimens by ELISA. All necessary reagents to measure 39 samples, in duplicate, are included in the kit. The sensitivity of this assay is approximately 0.08-5 mg/ml.